NOW ENROLLING PHASE 3

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Who can take part?

Below is a list of key eligibility criteria for the AMPLITUDE clinical research study. Please note other protocol defined inclusion and exclusion criteria apply.

Key inclusion criteria

  • All sexes aged 18–65 (Phase 2) or 12–65 (Phase 3)
  • APOL1 genotype of G1/G1, G2/G2, or G1/G2
  • Proteinuric kidney disease

Key exclusion criteria

  • Solid organ or bone marrow transplant
  • Uncontrolled hypertension
  • History of diabetes mellitus; a diagnosis of prediabetes is permitted
  • Known underlying cause of kidney disease,
    including but not limited to sickle cell disease